ChemistryBiologyMedicine

Wanzhen Dai, B. K. Tan, Jiamiao Hu

2026.8.30Advances in Protein Chemistry and Structural Biology

DOI: 10.1016/bs.apcsb.2025.08.004

tlooto Summary

This review offers a comprehensive and systematic overview of the AMP research, encompassing their origins, classification, and mechanisms of action, with a focus on the application of AMPs in food preservation and the emerging role of artificial intelligence in the identification and design of novel AMPs.

Abstract

Antimicrobial peptides (AMPs), which can be derived from diverse biological sources, exhibit a broad spectrum of inhibitory activity against bacteria, fungi, parasites, and viruses, positioning them as promising alternatives to traditional antibiotics. This review offers a comprehensive and systematic overview of the AMP research, encompassing their origins, classification, and mechanisms of action, with a focus on the application of AMPs in food preservation and the emerging role of artificial intelligence in the identification and design of novel AMPs.

Citation format

DAI, Wanzhen; TAN, B. K.; HU, Jiamiao. Antimicrobial peptides: Bridging mechanistic understanding and novel applications. Advances in Protein Chemistry and Structural Biology, 2026, 149: 93–113.