Skeletal Muscle Involvement in Systemic Immunoglobulin Light Chain Amyloidosis: Analysis of Clinical, Electrophysiological and Pathological Features in 11 Patients

In amyloid myopathy, muscle weakness was generally mild and exercise intolerance was a common feature probably attributable to underlying vascular pathology, and Muscle biopsies revealed mild inflammation and necrosis, accompanied by uneven granular C5b‐9 deposition in intramuscular vessels, a pattern that may serve as a clue for amyloidosis.