W. Park, Beomsu Kim, Gahee Song, Sang Hee Kim, Jin-Hyung Kim, Ja Yeon Park, Se Jin Jung, Wenjun Jiao, Jisoo Han, Taekyoung Kong, Kwang Seok Ahn, Hyun Jeong Kwak, Jae-Young Um
tlooto Summary
The potential of ellagic acid (EA) to mitigate cancer‐induced fat loss is investigated and it is found that it has the potential to mitigate cancer cachexia.
Abstract
Cancer cachexia is a syndrome characterized by significant weight loss, particularly of adipose tissue, which negatively impacts patient survival. Pharmacological approaches to prevent this abnormal fat reduction remain poorly defined. This study investigated the potential of ellagic acid (EA) to mitigate cancer‐induced fat loss.
Citation format
PARK, W., et al. Ellagic acid alleviates abnormal fat reduction by activating the RXRβ–PPARγ pathways in a CT26 tumour‐induced cachexia mouse model. Journal of Cachexia Sarcopenia and Muscle, 2026, 17(1): e70176.