Non‐Functional Paraganglioma of the Urinary Bladder: A Rare Cause of Bladder Tumor

ABSTRACT Introduction Paragangliomas of the urinary bladder (PUBs) are rare neuroendocrine tumors, representing less than 0.06% of all bladder neoplasms. While most are functional and associated with catecholamine excess, approximately 15% are non‐functional, often presenting asymptomatically and discovered incidentally. Due to their rarity, standardized management guidelines are lacking. Case Presentation We report a 57‐year‐old female evaluated for ureterolithiasis who was incidentally found to have a 1.5 cm posterior bladder lesion. Biopsy confirmed paraganglioma. Functional studies, including plasma and urinary metanephrines, were negative, establishing a non‐functional tumor. DOTATATE PET/CT and genetic testing excluded metastasis and hereditary syndromes. At planned transurethral resection, no residual lesion was identified, and pathology was benign. The patient remains asymptomatic on follow‐up. Conclusion This case illustrates the diagnostic challenges of non‐functional PUBs and emphasizes the importance of multidisciplinary evaluation and vigilant follow‐up in the absence of standardized management strategies.