Xinni Zhou, Xiaojuan Chi, Benqun Peng, Ming Gao, Ning Li, Lu Liu, J. Zeng, Yuxin Li, Yuzhang Chen, Song Wang
tlooto Summary
Influenza virus infection significantly induces the expression of lncRNA GAS5 via type I/III interferons and IL-6 signal pathways via type I/III interferons and IL-6 signal pathways.
Abstract
Highlights • Influenza virus infection significantly induces the expression of lncRNA GAS5 via type I/III interferons and IL-6 signal pathways.• LncRNA GAS5 can encode a critical micropeptide GAS5-P50 which facilitates influenza virus replication.• GAS5-pP50 interacts with NOTUM to promote the activation of the Wnt/β-catenin pathway.
Citation format
ZHOU, Xinni, et al. The lncrna gas5-encoded micropeptide facilitates influenza virus replication through modulation of the wnt/β-catenin signaling pathway. Current Research in Microbial Sciences, 2026, 10: 100559.