MedicineBiology

Jie Niu, Long Wang, Ji Qi, G. Lu

2026.1.29JOURNAL OF GENE MEDICINE

DOI: 10.1002/jgm.70085

tlooto Summary

This study highlighted the crucial role of OXPHOS in maintaining tendon homeostasis and suggested potential therapeutic strategies targeting the OXPHOS pathway.

Abstract

Chronic tendon injuries, characterized by persistent pain, reduced flexibility, and impaired function, pose a significant clinical challenge. Current therapeutic strategies for these injuries are limited. This study highlighted the crucial role of OXPHOS in maintaining tendon homeostasis and suggested potential therapeutic strategies targeting the OXPHOS pathway.

Citation format

NIU, Jie, et al. Single‐cell RNA sequencing and network pharmacology reveal the potential role of oxidative phosphorylation inactivation in diagnosing and treating chronic tendon injuries. JOURNAL OF GENE MEDICINE, 2026, 28(2): e70085.