Jiang Tan, Sisi Lei, Liang Zhao, Jiliang Hu, Yuqin Chen
2026.1.1NEPHROLOGY
tlooto Summary
This study aimed to investigate the potential causal relationship between GSTO1 and DN risk and found no clear relationship between GSTO1 and DN risk.
Abstract
Diabetic nephropathy (DN) is a major complication of diabetes mellitus and a leading cause of end‐stage renal disease (ESRD). Glutathione S‐transferase omega 1 (GSTO1) is implicated in redox regulation and inflammation, but its causal role in DN remains unclear. This study aimed to investigate the potential causal relationship between GSTO1 and DN risk.
Citation format
TAN, Jiang, et al. GSTO1 as a potential risk factor for diabetic nephropathy: Evidence from mendelian randomisation and multi‐omics analyses. NEPHROLOGY, 2026, 31(1): e70165.