Zhong-Da He, Zhi‐Gang Wang, Shu‐Lin Liu, Chuanming Yu
2026.1.1Advanced Therapeutics
tlooto Summary
Virus‐mimicking nanoparticles (VMNs) are drug delivery nanocarriers inspired by viruses, characterized by good biocompatibility, excellent in vivo stability, high cellular uptake efficiency, and significant tumor accumulation.
Abstract
Cancer is one of the major diseases threatening human health and life, and the development of cancer treatment methods is crucial for patient prognosis. Virus‐mimicking nanoparticles (VMNs) are drug delivery nanocarriers inspired by viruses, characterized by good biocompatibility, excellent in vivo stability, high cellular uptake efficiency, and significant tumor accumulation. VMNs mimic the mechanism of viral infection of host cells to achieve precise drug release, holding great potential in overcoming the limitations of traditional cancer treatment methods. This article discusses the preparation strategies of VMNs, their functionalities, and cancer treatment methods based on VMNs, including oxidative therapy, immunotherapy, and heat therapy, and explores the future development trends of VMNs.
Citation format
HE, Zhong-Da, et al. Development of cancer treatment strategies based on virus‐mimicking nanoparticles. Advanced Therapeutics, 2026, 9(1).