BiologyMaterials ScienceMedicine

Natalie J. Guzikowski, Camille S Wang, E. Kavalali

2026.1.1Advances in Neurobiology

DOI: 10.1007/978-3-032-12594-1_8

tlooto Summary

A basic design principle where the single synapse is a highly ordered and compartmentalized unit that by the functional nano-segregation of distinct forms of neurotransmission shapes synaptic efficacy, determines neurotransmission reliability, and tunes plasticity is supported.

Abstract

Within the single micron of the synapse, three distinct modes of neurotransmission, driven by synchronous, asynchronous, and spontaneous neurotransmitter release, occur concurrently. In this chapter, we discuss the synaptic nano-organization comprised of...

Citation format

GUZIKOWSKI, Natalie J.; WANG, Camille S; KAVALALI, E. Functional nano-segregation of distinct forms of neurotransmission. Advances in Neurobiology, 2026, 48: 217–257.