Relationship between dyslipidemia and diabetic retinopathy

Objective To investigate the relationship between diabetic retinopathy(DR) and dyslipidemia.Methods With large sample and multicenter study design,totally 603 patients had been observed with routine ocular examination and fluorescence fundus angiography to definite the stage of DR,pre-clinical phase 166 cases,non-proliferative phase 296 cases,proliferative phase 141 cases.The serum lipids,including triglycerides (TG),total cholesterol (TCH),high-density lipoprotein (HDL) and the plasma low-density lipoprotein (LDL) were tested.Results There was no statistic difference in TG,TCH,HDL and LDL among different phases(P0.05),but the average level of TG in every group went beyond normal value(0.56～1.70 mmol·L-1).After assessing the abnormality rate with the normal value criteria,the differences among HDL,LDL and TG were not statistic significance(P0.05).But difference of TCH abnormality rate had statistical significance(P0.05).There was obvious abnormality of TG and TCH in different phases.Moreover,the more DR severity condition level,the more increasing tendency of TCH and TG.Conclusion Dyslipidemia could promote the occurrence and development of DR.We should make a good lipids control in the prevention and treatment of DR.