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HIF-1α siRNA leads to apoptosis of pancreatic cancer cells under hypoxic conditions

Chuan-min Chen, Jianqiu Chen, Jinjin Sun

2009.5.30Chinese Journal of Clinical Oncology

DOI: 10.1007/s11805-009-0010-5

tlooto Summary

Under hypoxic conditions, Hif-1α plays a key role in the proliferation of MiaPaCa2 cells, and inhibition of HIF-1 α expression can lead to Mia PaCa2 cell apoptosis.

Abstract

Abstract is not available.

Citation format

CHEN, Chuan-min; CHEN, Jianqiu; SUN, Jinjin. HIF-1α sirna leads to apoptosis of pancreatic cancer cells under hypoxic conditions. Chinese Journal of Clinical Oncology, 2009, 6: 10–15.