Environmental ScienceMedicine

Toxicology and Carcinogenesis Studies of Hydrochlorothiazide (CAS No. 58-93-5) in F344/N Rats and B6C3F1 Mice (Feed Studies).

tlooto Summary

Renal mineralization was dose related and judged to be minimal to mild at the lowest dose and mineralization in the kidney was observed in all dosed rats and because of this, additional 13-week studies in rats were conducted at lower dietary concentrations.

Abstract

Abstract is not available.

Citation format

BUCHER, J. Toxicology and carcinogenesis studies of hydrochlorothiazide (CAS no. 58-93-5) in F344/N rats and B6C3F1 mice (feed studies). National Toxicology Program Technical Report Series, 1989, 357: 1–194.