ChemistryMedicine

T. Chan, Robert Hilgraf, K. Sharpless, V. Fokin

2004.7.30ORGANIC LETTERS

DOI: 10.1021/ol0493094

tlooto Summary

The C3-symmetric derivative of polytriazolylamines, TBTA, was shown to be a powerful stabilizing ligand for copper(I), protecting it from oxidation and disproportionation, while enhancing its catalytic activity.

Abstract

Polytriazolylamines were synthesized by the copper(I)-catalyzed ligation of azides and alkynes. The C3-symmetric derivative, TBTA, was shown to be a powerful stabilizing ligand for copper(I), protecting it from oxidation and disproportionation, while enhancing its catalytic activity.

Citation format

CHAN, T., et al. Polytriazoles as copper(i)-stabilizing ligands in catalysis. ORGANIC LETTERS, 2004, 6 17: 2853–5.