Open AccessMedicineBiology

P. Bercik, A. Park, D. Sinclair, A. Khoshdel, J. Lu, X. Huang, Y. Deng, P. Blennerhassett, M. Fahnestock, D. Moine, B. Berger, J. Huizinga, W. Kunze, P. McLean, G. Bergonzelli, S. Collins, Eduardo Verdu

2011.12.1NEUROGASTROENTEROLOGY AND MOTILITY

DOI: 10.1111/j.1365-2982.2011.01796.x

tlooto Summary

The probiotic Bifidobacterium longum NCC3001 normalizes anxiety‐like behavior and hippocampal brain derived neurotrophic factor (BDNF) in mice with infectious colitis and test whether the anxiolytic effect of B. longum involves vagal integrity, and changes in neural cell function.

Abstract

Background  The probiotic Bifidobacterium longum NCC3001 normalizes anxiety‐like behavior and hippocampal brain derived neurotrophic factor (BDNF) in mice with infectious colitis. Using a model of chemical colitis we test whether the anxiolytic effect of B. longum involves vagal integrity, and changes in neural cell function.

Citation format

BERCIK, P., et al. The anxiolytic effect of bifidobacterium longum NCC3001 involves vagal pathways for gut–brain communication. NEUROGASTROENTEROLOGY AND MOTILITY, 2011, 23.