MedicineBiology

Leptin enters the brain by a saturable system independent of insulin.

W. Banks, A. Kastin, Weitao Huang, J. Jaspan, L. Maness

1996.12.31PEPTIDES

DOI: 10.1016/0196-9781(96)00025-3

tlooto Summary

Results show that leptin is transported intact from blood to brain by a saturable system and inhibited the influx of 125I-leptin in a dose-dependent manner whereas unlabeled tyrosine and insulin, which have saturable transport systems, were without effect.

Abstract

Abstract is not available.

Citation format

BANKS, W., et al. Leptin enters the brain by a saturable system independent of insulin. PEPTIDES, 1996, 17 2: 305–11.