Open AccessMedicine

D. Khanna, D. Furst, P. Clements, Y. Allanore, M. Baron, L. Czirjak, O. Distler, I. Foeldvari, M. Kuwana, M. Matucci-Cerinic, M. Mayes, T. Medsger, P. Merkel, J. Pope, J. Seibold, V. Steen, W. Stevens, C. Denton

2017.1.1Journal of Scleroderma and Related Disorders

DOI: 10.5301/jsrd.5000231

tlooto Summary

This state-of-art review provides a historical perspective of the development of the modified Rodnan skin score, summarizes the performance of mRSS as an outcome measure, provides guidance on assessingmRSS, and makes recommendations for incorporation of the mR SS into clinical trials.

Abstract

The modified Rodnan skin score (mRSS) is a measure of skin thickness and is used as a primary or secondary outcome measure in clinical trials of systemic sclerosis (scleroderma). This state-of-art review provides a historical perspective of the development of the mRSS, summarizes the performance of mRSS as an outcome measure, provides guidance on assessing mRSS, and makes recommendations for incorporation of the mRSS into clinical trials.

Citation format

KHANNA, D., et al. Standardization of the modified rodnan skin score for use in clinical trials of systemic sclerosis. Journal of Scleroderma and Related Disorders, 2017, 2: 11–18.