Medicine

BRAF and NRAS mutations in melanoma and melanocytic nevi

J. Poynter, James T. Elder, D. Fullen, R. Nair, M. Soengas, T. Johnson, B. Redman, N. Thomas, S. Gruber

2006.8.1MELANOMA RESEARCH

DOI: 10.1097/01.cmr.0000222600.73179.f3

tlooto Summary

The data support the evidence that the mitogen-activated protein kinase pathway is upregulated in a large percentage of melanocytic lesions, but these mutations are not sufficient for malignant transformation.

Abstract

Abstract is not available.

Citation format

POYNTER, J., et al. BRAF and NRAS mutations in melanoma and melanocytic nevi. MELANOMA RESEARCH, 2006, 16: 267–273.