MedicineEnvironmental Science

Myocardial Microvascular Inflammatory Endothelial Activation in Heart Failure With Preserved Ejection Fraction.

C. Franssen, Sophia Chen, A. Unger, H. I. Korkmaz, G. D. De Keulenaer, C. Tschöpe, A. Leite-Moreira, R. Musters, H. Niessen, W. Linke, W. Paulus, N. Hamdani

2016.4.1JACC-Heart Failure

DOI: 10.1016/j.jchf.2015.10.007

tlooto Summary

HFpEF is associated with coronary microvascular endothelial activation and oxidative stress, which lead to a reduction of NO-dependent signalling from endothelial cells to cardiomyocytes, which can contribute to the highCardiomyocyte stiffness and hypertrophy observed in HFpEF.

Abstract

Abstract is not available.

Citation format

FRANSSEN, C., et al. Myocardial microvascular inflammatory endothelial activation in heart failure with preserved ejection fraction. JACC-Heart Failure, 2016, 4 4: 312–24.