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Nrf2-Keap1 defines a physiologically important stress response mechanism.

H. Motohashi, Masayuki Yamamoto

2004.11.1TRENDS IN MOLECULAR MEDICINE

DOI: 10.1016/j.molmed.2004.09.003

tlooto Summary

Analysis of keap1-knockout mice provides solid evidence that Keap1 acts as a negative regulator of Nrf2 and as a sensor of xenobiotic and oxidative stresses.

Abstract

Abstract is not available.

Citation format

MOTOHASHI, H.; YAMAMOTO, Masayuki. Nrf2-keap1 defines a physiologically important stress response mechanism. TRENDS IN MOLECULAR MEDICINE, 2004, 10 11: 549–57.