tlooto
Sign up
ChemistryMedicine

In Situ Neutralization in Boc-chemistry Solid Phase Peptide Synthesis

M. Schnölzer, P. Alewood, Alun Jones, D. Alewood, S. Kent

2007.1.10International Journal of Peptide Research and Therapeutics

DOI: 10.1007/s10989-006-9059-7

tlooto Summary

The in situ neutralization protocols gave a significant increase in the efficiency of chain assembly, especially for “difficult” sequences arising from sequence-dependent peptide chain aggregation in standard (neutralization prior to coupling) Boc-chemistry SPPS protocols or in Fmoc- chemistry SPPS.

Abstract

Abstract is not available.

Citation format

SCHNÖLZER, M., et al. In situ neutralization in boc-chemistry solid phase peptide synthesis. International Journal of Peptide Research and Therapeutics, 2007, 13: 31–44.