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MHC-restricted cytotoxic T cells: studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness.

R. Zinkernagel, P. Doherty

1979Advances in Immunology

DOI: 10.1016/s0065-2776(08)60262-x

tlooto Summary

This chapter focuses on the important discovery that virus-specific cytotoxic T cells are dually specific for virus and for a self cell surface antigen encoded by the major histocompatibility complex (MHC).

Abstract

Abstract is not available.

Citation format

ZINKERNAGEL, R.; DOHERTY, P. MHC-restricted cytotoxic t cells: Studies on the biological role of polymorphic major transplantation antigens determining t-cell restriction-specificity, function, and responsiveness. Advances in Immunology, 1979, 27: 51–177.