Viral infections associated with Kawasaki disease

Kawasaki disease (KD) is a febrile, acute, and self-limiting form of vasculitis that affects middle-sized arteries, particularly coronary arteries. It is generally reported in children younger than five years of age. A diagnosis of KD is based on the presence of a prolonged fever, accompanied by four of the following five findings: conjunctival injection, oral changes, cervical lymphadenopathy, extremity changes, and polymorphous rash. The etiopathogenesis of KD remains unclear, and it has been suggested that various infectious agents may trigger KD development in genetically susceptible individuals (1). Additionally, several features of KD resemble the features of viral infectious diseases, such as influenza, Epstein-Barr virus (EBV), and adenovirus. Therefore, the differential diagnosis of KD may be challenging for clinicians. In this study, we