S. Caroff
1980.3.1Adverse Drug Reaction Bulletin
tlooto Summary
The author presents a detailed review of the clinical characteristics and differential diagnosis of the NMS as described in the world literature to enhance knowledge of neuroleptic pharmacology and produce more effective means of prevention and treatment.
Abstract
Since the initial description of neuroleptic malignant syndrome (NMS) 40 years ago, a wealth of clinical data has accumulated on the manifestations, course, treatment, and pathogenesis of this uncommon but serious and potentially lethal drug reaction. Nevertheless, vigilance must be maintained, as this disorder remains obscure to many practising physicians. Here, we review the clinical features of NMS to enhance patient safety and reduce physician liability whenever antipsychotic drugs are administered.
Citation format
CAROFF, S. The neuroleptic malignant syndrome. Adverse Drug Reaction Bulletin, 1980, 41 3: 79–83.