Medicine

C. Annweiler, J. Souberbielle, A. Schott, L. De decker, G. Berrut, O. Beauchet

2011.9.1Geriatrie et Psychologie Neuropsychiatrie du Vieillissement

DOI: 10.1684/pnv.2011.0288

tlooto Summary

The supplementation for correction of hypovitaminosis D positively impacts bone and non-bone morbidities - such as risks of falls and fractures - and reduces the mortality rate.

Abstract

Vitamin D is a secosteroid hormone. Vitamin D receptors are present in the majority of body tissues. The manifestations of hypovitaminosis D - linked to dysfunction of target tissues - are various, including osteoporosis, cancer, tuberculosis, hypertension, multiple sclerosis, depression, dementia, sarcopenia, propensity to fall… The serum 25-hydroxyvitamin D threshold value to avoid these adverse health events is around 30 ng/mL. Only 15% of the elderly reach this target concentration. For the remaining 85% with no supplements, the severity of hypovitaminosis D appears to be a biomarker of chronic diseases and of frailty. Conversely, the supplementation for correction of hypovitaminosis D positively impacts bone and non-bone morbidities - such as risks of falls and fractures - and reduces the mortality rate. A daily intake of at least 800-1,000 IU supplemental vitamin D(3) per day is the key.

Citation format

ANNWEILER, C., et al. [Vitamin d in the elderly: 5 points to remember]. Geriatrie et Psychologie Neuropsychiatrie du Vieillissement, 2011, 9 3: 259–67.