ChemistryMedicine

Validation of bioanalytical LC-MS/MS assays: evaluation of matrix effects.

A. Van Eeckhaut, K. Lanckmans, S. Sarre, I. Smolders, Y. Michotte

2009.8.1JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

DOI: 10.1016/j.jchromb.2009.01.003

tlooto Summary

In this review, the influence of matrix effects on bioanalytical LC-MS/MS methods is discussed and illustrated with some examples, and possible solutions to reduce or eliminate matrix effects are highlighted.

Abstract

Abstract is not available.

Citation format

EECKHAUT, A. Van, et al. Validation of bioanalytical LC-MS/MS assays: Evaluation of matrix effects. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2009, 877 23: 2198–207.