MedicineBiology

Alterations in DNA methylation: a fundamental aspect of neoplasia.

S. Baylin, J. Herman, J. Graff, P. Vertino, J. Issa

1998Advances in Cancer Research

DOI: 10.1016/s0065-230x(08)60702-2

tlooto Summary

A model is proposed wherein tumor progression results from episodic clonal expansion of heterogeneous cell populations driven by continuous interaction between these methylation abnormalities and classic genetic changes.

Abstract

Abstract is not available.

Citation format

BAYLIN, S., et al. Alterations in DNA methylation: A fundamental aspect of neoplasia. Advances in Cancer Research, 1998, 72: 141–96.