Supakanya Wongrakpanich, A. Wongrakpanich, Katherine Melhado, J. Rangaswami
2018.2.1Aging and Disease
tlooto Summary
The pharmacodynamics and pharmacokinetics, current guidelines for NSAIDs use, adverse effect profile, and drug interaction of NSAIDs and commonly used medications in the elderly are reviewed.
Abstract
NSAIDs, non-steroidal anti-inflammatory drugs, are one of the most commonly prescribed pain medications. It is a highly effective drug class for pain and inflammation; however, NSAIDs are known for multiple adverse effects, including gastrointestinal bleeding, cardiovascular side effects, and NSAID induced nephrotoxicity. As our society ages, it is crucial to have comprehensive knowledge of this class of medication in the elderly population. Therefore, we reviewed the pharmacodynamics and pharmacokinetics, current guidelines for NSAIDs use, adverse effect profile, and drug interaction of NSAIDs and commonly used medications in the elderly.
Citation format
WONGRAKPANICH, Supakanya, et al. A comprehensive review of non-steroidal anti-inflammatory drug use in the elderly. Aging and Disease, 2018, 9: 143–150.