Group 2 innate lymphoid cells are elevated and activated in chronic rhinosinusitis with nasal polyps
J. Poposki, Aiko I. Klingler, B. Tan, P. Soroosh, Homayon Banie, Gavin M. Lewis, K. Hulse, W. Stevens, Anju T Peters, L. Grammer, R. Schleimer, Kevin C. Welch, Stephanie S. Smith, D. Conley, Joseph R. Raviv, J. Karras, O. Akbari, R. Kern, A. Kato
tlooto Summary
Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by type 2 inflammation with high levels of Th2 cytokines, and the presence of various types of ILC in CRS is poorly understood.
Abstract
Chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) is characterized by type 2 inflammation with high levels of Th2 cytokines. Although T helper cytokines are released from T cells, innate lymphoid cells (ILC) are also known to produce high levels of the same cytokines. However, the presence of various types of ILC in CRS is poorly understood.
Citation format
POPOSKI, J., et al. Group 2 innate lymphoid cells are elevated and activated in chronic rhinosinusitis with nasal polyps. Immunity Inflammation and Disease, 2017, 5: 233–243.