Okra (Abelmoscus esculentus) Improved Islets Structure, and Down-Regulated PPARs Gene Expression in Pancreas of High-Fat Diet and Streptozotocin-Induced Diabetic Rats.

Okra supplementation significantly decreased the elevated levels of FBS, total cholesterol, and TG and attenuated homeostasis model assessment of basal insulin resistance (HOMA-IR) index in diabetic rats and down-regulation of PPARs genes in the pancreas of diabetic rats after treatment with okra demonstrates that okra may improve glucose homeostas and β-cells impairment in diabetes through a PPAR-dependent mechanism.