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ChemistryMedicine

Structural insights into the catalytic mechanism of cyclophilin A

B. R. Howard, F. Vajdos, Su Li, W. Sundquist, C. Hill

2003.6.1Nature Structural Biology

DOI: 10.1038/nsb927

tlooto Summary

Crystal structures of CypA in complex with HIV-1 CA protein variants that bind preferentially with the substrate proline residue in either the cis or the trans conformation are reported.

Abstract

Abstract is not available.

Citation format

HOWARD, B. R., et al. Structural insights into the catalytic mechanism of cyclophilin a. Nature Structural Biology, 2003, 10: 475–481.