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Neutrophil extracellular traps

M. Demers, Denisa D Wagner

2013.2.1OncoImmunology

DOI: 10.4161/onci.22946

tlooto Summary

The role of NETs in cancer biology and tumor progression may prove much more than an unfortunate side effect of cancer.

Abstract

Cancers prime neutrophils to release extracellular DNA traps through the systemic release of granulocyte colony-stimulating factor (G-CSF). We recently showed that these circulating neutrophil extracellular traps (NETs) promote the establishment of a pro-thrombotic state. The role of NETs in cancer biology and tumor progression may prove much more than an unfortunate side effect of cancer.

Citation format

DEMERS, M.; WAGNER, Denisa D. Neutrophil extracellular traps. OncoImmunology, 2013, 2.