BiologyMedicine

Bacterial cupredoxin azurin as an inducer of apoptosis and regression in human breast cancer

V. Punj, Suchita Bhattacharyya, D. Saint-Dic, C. Vasu, E. Cunningham, J. Graves, Tohru Yamada, A. Constantinou, K. Christov, B. White, Gang Li, D. Majumdar, A. Chakrabarty, T. K. Gupta

2004.3.25ONCOGENE

DOI: 10.1038/sj.onc.1207376

tlooto サマリー

In conclusion, azurin blocks breast cancer cell proliferation and induces apoptosis through the mitochondrial pathway both in vitro and in vivo, thereby suggesting a potential chemotherapeutic application of this bacterial cupredoxin for the treatment of breast cancer.

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引用形式

PUNJ, V., et al. Bacterial cupredoxin azurin as an inducer of apoptosis and regression in human breast cancer. ONCOGENE, 2004, 23: 2367–2378.