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NF-κB: a key role in inflammatory diseases

P. Tak, G. Firestein

2001JOURNAL OF CLINICAL INVESTIGATION

DOI: 10.1172/jci11830

tlooto Summary

The specificity of various NF-κB proteins, their role in inflammatory disease, the regulation of NF-β proteins and IκB activity by IκBs and IkkB kinase, and the development of therapeutic strategies aimed at inhibition are discussed.

Abstract

Abstract is not available.

Citation format

TAK, P.; FIRESTEIN, G. NF-κB: A key role in inflammatory diseases. JOURNAL OF CLINICAL INVESTIGATION, 2001, 107: 7–11.