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Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia

D. Rolnik, D. Wright, L. Poon, N. O’Gorman, A. Syngelaki, C. de Paco Matallana, R. Akolekar, S. Cicero, D. Janga, Mandeep Singh, F. Molina, N. Persico, J. Jani, W. Plasencia, G. Papaioannou, K. Tenenbaum‐Gavish, H. Meiri, S. Gizurarson, K. Maclagan, K. Nicolaides

2017.6.28OBSTETRICAL & GYNECOLOGICAL SURVEY

DOI: 10.1097/01.ogx.0000528015.09400.25

tlooto 摘要

Treatment with low‐dose aspirin in women at high risk for preterm preeclampsia resulted in a lower incidence of this diagnosis than placebo, and there were no significant between‐group differences in the incidence of neonatal adverse outcomes or other adverse events.

摘要

(Abstracted from N Engl J Med 2017;377:613–622) Since 1979, multiple studies have shown that low-dose aspirin in pregnancy can lower the occurrence of preeclampsia. Subsequent studies have shown that doses greater than 100 mg/d started before 16 weeks of gestation are most effective.

引用格式

ROLNIK, D., et al. Aspirin versus placebo in pregnancies at high risk for preterm preeclampsia. OBSTETRICAL & GYNECOLOGICAL SURVEY, 2017.