Jianming Lü, P. Lin, Q. Yao, Changyi J. Chen
tlooto Summary
Inhibition of free radical generating enzymes is inhibition of internal antioxidant enzymes and prevention of lipid peroxidation is prevention of DNA damage and protein modification.
Abstract
• Introduction • Free radical scavenging ‐ Scavenging superoxide and other ROS ‐ Scavenging hydroxyl radical and other ROS ‐ Stable radical scavenging • Metal ion (Fe2+, Fe3+, Cu2+ and Cu+) chelating • Inhibition of free radical generating enzymes • Activation of internal antioxidant enzymes • Prevention of lipid peroxidation • Prevention of DNA damage • Prevention of protein modification • Conclusions
Citation format
LÜ, Jianming, et al. Chemical and molecular mechanisms of antioxidants: Experimental approaches and model systems. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2009, 14: 840–860.