BiologyComputer ScienceMedicine
T. Ideker, T. Galitski, Leroy Hood
tlooto Summary
The emergence of systems biology is described, as well as several examples of specific systems approaches.
Abstract
Systems biology studies biological systems by systematically perturbing them (biologically, genetically, or chemically); monitoring the gene, protein, and informational pathway responses; integrating these data; and ultimately, formulating mathematical models that describe the structure of the system and its response to individual perturbations. The emergence of systems biology is described, as are several examples of specific systems approaches.
Citation format
IDEKER, T.; GALITSKI, T.; HOOD, Leroy. A new approach to decoding life: Systems biology. Annual Review of Genomics and Human Genetics, 2001, 2: 343–72.