MedicineChemistry

Divya Dheer, Virender Singh, R. Shankar

2017.4.1BIOORGANIC CHEMISTRY

DOI: 10.1016/j.bioorg.2017.01.010

tlooto Summary

The present work aims to summarize the current approaches adopted for the synthesis of the 1,2,3-triazole and medicinal significance of these architectures as a lead structure for the discovery of drug molecules such as COX-1/COX-2 inhibitors, HIV protease inhibitors, CB1 cannabinoid receptor antagonist and much more which are in the pipeline of clinical trials.

Abstract

Abstract is not available.

Citation format

DHEER, Divya; SINGH, Virender; SHANKAR, R. Medicinal attributes of 1,2,3-triazoles: Current developments. BIOORGANIC CHEMISTRY, 2017, 71: 30–54.