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Human leptin stimulates proliferation and activation of human circulating monocytes.

J. Santos‐Álvarez, R. Goberna, V. Sánchez-Margalet

1999.5.25CELLULAR IMMUNOLOGY

DOI: 10.1006/cimm.1999.1490

tlooto Summary

It is shown that human leptin stimulates proliferation in a dose-dependent manner and functionally activates human circulating monocytes in vitro, by inducing the production of cytokines such as TNF-alpha and IL-6, and suggests that it may have a role as a proinflammatory cytokine.

Abstract

Abstract is not available.

Citation format

SANTOS‐ÁLVAREZ, J.; GOBERNA, R.; SÁNCHEZ-MARGALET, V. Human leptin stimulates proliferation and activation of human circulating monocytes. CELLULAR IMMUNOLOGY, 1999, 194 1: 6–11.