Identification of alpha-galactosyl and other carbohydrate epitopes that are bound by human anti-pig antibodies: relevance to discordant xenografting in man.

The results suggest that human anti-pig antibodies are mainly directed against alpha-galactosyl structures, andExtracorporeal immunoadsorption of human plasma through columns of the specific synthetic carbohydrate(s) might lead to depletion of anti-Pig antibodies and allow discordant xenografting in man.