Cognitive deficits in Parkinson’s disease

Neuropsychological investigations of patients with Parkinson’s disease have shown specific impairments even in the early stages of the disease, which include deficit of behavioural regulation in sorting or planning tasks, defective use of memory stores, and impaired manipulation of internal representation of visuospatial stimuli, suggesting a functional continuity or complementarity between the basal ganglia and association areas of the prefrontal cortex.