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BiologyMedicine

Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

L. Harrington, R. D. Hatton, Paul R. Mangan, Henrietta Turner, T. Murphy, K. Murphy, C. Weaver

2005.11.1NATURE IMMUNOLOGY

DOI: 10.1038/ni1254

tlooto Summary

Findings provide a basis for understanding how inhibition of IFN-γ signaling enhances development of pathogenic TH-17 effector cells that can exacerbate autoimmunity.

Abstract

Abstract is not available.

Citation format

HARRINGTON, L., et al. Interleukin 17–producing CD4+ effector t cells develop via a lineage distinct from the t helper type 1 and 2 lineages. NATURE IMMUNOLOGY, 2005, 6: 1123–1132.