N. Maruotti, F. Cantatore, E. Crivellato, A. Vacca, D. Ribatti
2007.5.1HISTOLOGY AND HISTOPATHOLOGY
tlooto Summary
In rheumatoid arthritis (RA) tissue macrophages are responsible for inducing inflammation, matrix destruction and angiogenesis, and an imbalance between these inducers and inhibitors of inflammation occurs.
Abstract
In rheumatoid arthritis (RA) tissue macrophages release growth factors, matrix metalloproteinases, cytokines, and chemokines. While in normal joints there is a balance between proinflammatory and anti-inflammatory cytokines, an imbalance between these inducers and inhibitors of inflammation occurs in RA, where macrophages are responsible for inducing inflammation, matrix destruction and angiogenesis.
Citation format
MARUOTTI, N., et al. Macrophages in rheumatoid arthritis. HISTOLOGY AND HISTOPATHOLOGY, 2007, 22 5: 581–6.