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Metabolism of L-Arginine by Myeloid-Derived Suppressor Cells in Cancer: Mechanisms of T cell suppression and Therapeutic Perspectives

Patrick Raber, A. Ochoa, P. Rodriguez

2012.8.1IMMUNOLOGICAL INVESTIGATIONS

DOI: 10.3109/08820139.2012.680634

tlooto Summary

Some of the most recent concepts of how MDSC expressing Arginase I may regulate T cell function in cancer are discussed and possible therapeutic interventions to overcome this inhibitory effect are suggested.

Abstract

Abstract is not available.

Citation format

RABER, Patrick; OCHOA, A.; RODRIGUEZ, P. Metabolism of l-arginine by myeloid-derived suppressor cells in cancer: Mechanisms of t cell suppression and therapeutic perspectives. IMMUNOLOGICAL INVESTIGATIONS, 2012, 41: 614–634.