Nano-size hydroxyapatite powders preparation by wet-chemical precipitation route

In this study, wet-chemical process was performed to prepare nano-size hydroxyapatite (HA) powders (≈10 nm) by varying concentration (low, medium and high) of the starting solutions in order to increase the amount of as-dried HA powders with different process conditions. Particle sizes and density were analyzed and differential thermal analysiswas used to determine the glass transition (T g ) and the onsetcrystallization (Tc) temperatures. XRD and SEM were performedto identify phases and microstructure. The wet-chemical precipitation using low concentration ofstarting solution under reflux environment could be the optimize process to induce the formation of hydroxyapatite rather than tricalcium phosphate even though obtaining a smaller amount of as-dried powders comparedto using high concentration. In addition, the density at 4.05 g/cm 3 and specific surface area at 89.58 m 2 /g as well as a uniform grain size morphology with a small size distribution can be achieved by using this route.