Open AccessChemistryEnvironmental ScienceMedicine

Koen Van Aken, L. Strekowski,, L. Patiny

2006.3.3Beilstein Journal of Organic Chemistry

DOI: 10.1186/1860-5397-2-3

tlooto Summary

A novel post-synthesis analysis tool is presented which evaluates quality of the organic preparation based on yield, cost, safety, conditions and ease of workup/purification based on assigning a range of penalty points to these parameters.

Abstract

A novel post-synthesis analysis tool is presented which evaluates quality of the organic preparation based on yield, cost, safety, conditions and ease of workup/purification. The proposed approach is based on assigning a range of penalty points to these parameters. This semi-quantitative analysis can easily be modified by other synthetic chemists who may feel that some parameters should be assigned different relative penalty points. It is a powerful tool to compare several preparations of the same product based on safety, economical and ecological features.

Citation format

AKEN, Koen Van; STREKOWSKI,, L.; PATINY, L. Ecoscale, a semi-quantitative tool to select an organic preparation based on economical and ecological parameters. Beilstein Journal of Organic Chemistry, 2006, 2.