BiologyComputer ScienceMedicine

Measurement of mRNA abundance using RNA-seq data: RPKM measure is inconsistent among samples

G. Wagner, Koryu Kin, Vincent J. Lynch

2012.8.8THEORY IN BIOSCIENCES

DOI: 10.1007/s12064-012-0162-3

tlooto-Zusammenfassung

It is argued that the intended meaning of RPKM is a measure of relative molar RNA concentration (rmc) and it is shown that for each set of transcripts the average rmc is a constant, namely the inverse of the number of transcripts mapped.

Abstract

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Zitationsformat

WAGNER, G.; KIN, Koryu; LYNCH, Vincent J. Measurement of mrna abundance using RNA-seq data: RPKM measure is inconsistent among samples. THEORY IN BIOSCIENCES, 2012, 131: 281–285.