Medicine

Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man.

L. Fischer, D. Culver, P. Tennant, A. Davis, Minsheng Wang, A. Castellano-Sanchez, J. Khan, Meraida Polak, J. Glass

2004.2.1EXPERIMENTAL NEUROLOGY

DOI: 10.1016/j.expneurol.2003.10.004

tlooto-Zusammenfassung

It is concluded that in this widely studied animal model of human ALS, and in this single human case, motor neuron pathology begins at the distal axon and proceeds in a "dying back" pattern.

Abstract

Abstract ist nicht verfügbar.

Zitationsformat

FISCHER, L., et al. Amyotrophic lateral sclerosis is a distal axonopathy: Evidence in mice and man. EXPERIMENTAL NEUROLOGY, 2004, 185 2: 232–40.