ChemistryMedicine

H. Beraldo, D. Gambino

2003.12.31MINI-REVIEWS IN MEDICINAL CHEMISTRY

DOI: 10.2174/1389557043487484

tlooto Summary

The more significant bioactivities of a variety of semicarbazones (anti-protozoa, anticonvulsant) and thiosemicarbazone and their metal complexes are reviewed together with proposed mechanisms of action and structure-activity relationships.

Abstract

The more significant bioactivities of a variety of semicarbazones (anti-protozoa, anticonvulsant) and thiosemicarbazones (antibacterial, antifungal, antitumoral, antiviral) and their metal complexes are reviewed together with proposed mechanisms of action and structure-activity relationships. Clinical or potential pharmacological applications of these versatile compounds are discussed.

Citation format

BERALDO, H.; GAMBINO, D. The wide pharmacological versatility of semicarbazones, thiosemicarba-zones and their metal complexes. MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2003, 4 1: 31–9.