Kena Zhang, Xiuhua Xu, F. Qing
tlooto Summary
Trifluoromethylthiolation is a growing area of study due to its importance in pharmaceuticals, agrochemicals and materials, with new progress and synthetic challenges being described.
Abstract
Abstract Compounds containing trifluoromethylthio group (SCF3) play an important role in pharmaceuticals, agrochemicals and materials due to its strong electron-withdrawing effect and extremely high lipophilicity. Very recently, trifluoromethylthiolation has received a great attention. In this review, the new progress of direct trifluoromethylthiolation is described. Furthermore, the synthetic challenge for trifluoromethylthiolation is also discussed.
Citation format
ZHANG, Kena; XU, Xiuhua; QING, F. Recent advances of direct trifluoromethylthiolation. CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2015, 35: 556.