The antibacterial effect in vitro of Kouyanqing and its ingredients

Objective To investigate the effect of Kouyanqing and its ingredients on the growth of intestinal dominant flora and opportunistic pathogens Streptococcus mutans and Streptococcus sanguis in mouth. Methods Live bacteria counting method based on the selective medium. Results 5% and 10% Kouyanqing and its ingredients showed obvious inhibitory effect on Staphylococcus aureus and Escherichia coli. The inhibitory effect of 5% and10% Kouyanqing and ingredients on the growth of Lactobacillus was not obvious,only 10% Flos Lonicerae runny paste had certain inhibitory effect. 10% Flos Lonicerae,Radix Scrophulariae and Kouyanqing had significant inhibitory effect on Streptococcus sanguis and Streptococcus mutans. 5% and 10% aspartate Ophiopogon japonicus extract could promote the growth of Bifidobacterium. Conclusion Kouyanqing and its ingredients have obvious inhibitory effect on Staphylococcus aureus,Escherichia coli,Streptococcus sanguis and Streptococcus mutans while no obvious inhibition on Lactobacillus,some ingredients of which can promote the growth of Bifidobacterium.